DIFFERENCES IN QUALITY OF LIFE OF PATIENTS MORE Cervical Cancer STADIUM AFTER CHEMOTHERAPY AND POST Radiotherapy

ABSTRACT: Background: Increasing the number of cervical cancer's survivor giving special attention to the impact of the disease and its treatment on patients's quality of life. Several treatment options for cervical cancer treatment, namely chemotherapy and radiotherapy has side effects that can cause changes in the quality of life of patients. Objective: Analyze the differences in the quality of life in patients with advanced stage cervical cancer post chemotherapy and post radiotherapy. Methods: The population in this study were all advanced stage cervical cancer patients post chemotherapy and post radiotherapy at the RSUP Dr. Sardjito and RSUP Dr. Kariadi in July 2015-January 2016. This study used consecutive sampling with 60 respondents of cervical cancer patients post chemotherapy and 34 respondent patients with cervical cancer post radiotherapy. This used EORTC QLQ-C30 in Indonesian version. The patients quality of life was measured within 1 week after completing the first cycle of chemotherapy or radiotherapy. Results: Patients's quality of life with cervical cancer post chemotherapy has mean value of functional scale >50 and the mean scale public health 59,98 +-15,116, and mean value of symptom scale <50 except for fatique, nausea and vomiting, and loss of appetite. Patients's quality of life with cervical cancer post radiotherapy has mean value of functional scale >50 and the mean scale public health 70,97+-16,144, and mean value of symptom scale <50 except for fatique. Some life quality scale that has a value of p <0.05 is the general health scale (p=0.016), nausea and vomiting (p = 0.000), and the symptoms of loss of appetite (p = 0.003). Conclusion: There is significant differences between patients quality of life with advanced cervical cancer post chemotherapy and post radiotherapy on a scale public health, symptoms of nausea and vomiting, and loss of appetite.